{"id":50060,"date":"2025-08-04T11:33:45","date_gmt":"2025-08-04T06:03:45","guid":{"rendered":"https:\/\/blog.ultrahuman.com\/blog\/?p=50060"},"modified":"2025-08-04T11:33:45","modified_gmt":"2025-08-04T06:03:45","slug":"hormones-explained-what-blood-testing-can-reveal-about-your-health","status":"publish","type":"post","link":"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/","title":{"rendered":"Hormones explained: what blood testing can reveal about your health"},"content":{"rendered":"\n<p>Hormones are chemical signals that coordinate the way your body works. They\u2019re produced by glands like the brain, adrenal glands, ovaries, or testes, and travel through your bloodstream to deliver instructions to different organs and tissues.<\/p>\n\n\n\n<p>The hormone panel in <a href=\"https:\/\/www.ultrahuman.com\/blood-vision\/buy\/us\/\">Blood Vision<\/a> measures a targeted set of hormones related to energy, fertility, recovery, and resilience. Many of these are shared across the male and female panels. Others, like estradiol and AMH, are specific to women\u2019s physiology.<\/p>\n\n\n\n<p><strong>Read more <a href=\"https:\/\/blog.ultrahuman.com\/blog\/introducing-blood-vision-with-ultratrace\/\">about Blood Vision here<\/a>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-quick-look-blood-vision-hormone-panel-explained\">Quick look: Blood Vision Hormone Panel explained<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th><strong>Hormone<\/strong><\/th><th><strong>Panel<\/strong><\/th><th><strong>What it shows<\/strong><\/th><th><strong>What high levels may indicate<\/strong><\/th><th><strong>What low levels may indicate<\/strong><\/th><\/tr><\/thead><tbody><tr><td><strong>Testosterone (total &amp; free)<\/strong><\/td><td>Male &amp; female<\/td><td>Overall and active androgen levels<\/td><td>PCOS (in women), anabolic steroid use, tumors, low SHBG<\/td><td>Aging, testicular\/ovarian failure, high SHBG, pituitary dysfunction<\/td><\/tr><tr><td><strong>SHBG<\/strong><\/td><td>Male &amp; female<\/td><td>Amount of bound vs. free testosterone\/estrogen<\/td><td>High estrogen, hyperthyroidism, liver dysfunction<\/td><td>Insulin resistance, obesity, hypothyroidism<\/td><\/tr><tr><td><strong>DHEA-S<\/strong><\/td><td>Male &amp; female<\/td><td>Adrenal androgen reserve<\/td><td>PCOS, adrenal hyperplasia, supplement overuse<\/td><td>Adrenal fatigue, chronic stress, aging<\/td><\/tr><tr><td><strong>Cortisol<\/strong><\/td><td>Male &amp; female<\/td><td>Stress response and circadian rhythm<\/td><td>Chronic stress, inflammation, HPA axis dysregulation<\/td><td>Adrenal insufficiency, burnout, pituitary suppression<\/td><\/tr><tr><td><strong>Luteinizing hormone (LH)<\/strong><\/td><td>Male &amp; female<\/td><td>Brain\u2013gonad signal: testosterone or ovulation trigger<\/td><td>PCOS, testicular\/ovarian failure<\/td><td>Pituitary\/hypothalamic dysfunction, suppressed reproductive axis<\/td><\/tr><tr><td><strong>Follicle-stimulating hormone (FSH)<\/strong><\/td><td>Male &amp; female<\/td><td>Brain\u2013gonad signal: sperm or egg development<\/td><td>Menopause, reduced ovarian\/testicular function<\/td><td>Pituitary suppression, undernutrition, stress<\/td><\/tr><tr><td><strong>Prolactin<\/strong><\/td><td>Male &amp; female<\/td><td>Regulation of reproductive hormone production<\/td><td>Stress, medications, prolactinoma<\/td><td>Rare, but can impair reproductive signaling<\/td><\/tr><tr><td><strong>Estradiol (E2)<\/strong><\/td><td>Female only<\/td><td>Estrogen status, menstrual cycle, mood, bone health<\/td><td>Estrogen dominance, tumors, PCOS<\/td><td>Perimenopause, ovarian failure, irregular cycles<\/td><\/tr><tr><td><strong>Anti-M\u00fcllerian hormone (AMH)<\/strong><\/td><td>Female only<\/td><td>Ovarian reserve \u2014 estimate of remaining egg supply<\/td><td>PCOS (many immature follicles, poor ovulation)<\/td><td>Reduced fertility potential, perimenopause<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-testosterone-total-amp-free\">Testosterone (total &amp; free)<\/h3>\n\n\n\n<p>Testosterone is a sex hormone classified as an androgen, meaning it promotes male traits like muscle growth, facial hair, and deep voice \u2060\u2013 but it&#8217;s important in both sexes. It&#8217;s produced mainly in the testes in men and in smaller amounts by the ovaries and adrenal glands in women<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Total testosterone<\/strong> refers to all testosterone in the blood, including the part that\u2019s \u201cbound\u201d (attached to carrier proteins like SHBG and albumin) and the \u201cfree\u201d portion.<\/li>\n\n\n\n<li><strong>Free testosterone<\/strong> is the fraction that is not bound to proteins and is available to enter cells and activate testosterone receptors. This is the biologically active part that actually does the work.<\/li>\n<\/ul>\n\n\n\n<p><strong>Why it matters:<\/strong><br>Symptoms like fatigue, low libido, muscle loss, or poor recovery often track more closely with free testosterone, not total. That\u2019s because high levels of SHBG can lock away too much testosterone, making it unavailable for use. A normal total level can mask a functional deficiency if your free testosterone is low.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-shbg-sex-hormone-binding-globulin\">SHBG (sex hormone\u2013binding globulin)<\/h3>\n\n\n\n<p>SHBG is a protein made in the liver that binds tightly to sex hormones like testosterone and estradiol. When bound, these hormones are inactive \u2060\u2013 they can\u2019t enter cells or exert effects.<\/p>\n\n\n\n<p><strong>Why it matters:<\/strong><br>High SHBG means less free testosterone is available, which can lead to symptoms of low T even if your total level looks fine. SHBG tends to rise with high estrogen, thyroid hormone excess, or liver disease. Low SHBG may occur in insulin resistance, obesity, or hypothyroidism \u2014 which can increase free testosterone but also point to deeper metabolic problems.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-dhea-s-dehydroepiandrosterone-sulfate\">DHEA-S (dehydroepiandrosterone sulfate)<\/h3>\n\n\n\n<p><br>DHEA-S is made by the adrenal gland and serves as a precursor hormone. That means it gets converted into other hormones \u2014 mainly testosterone and estrogen \u2014 in various tissues. The \u201cS\u201d stands for sulfate, which helps stabilize it in the bloodstream for longer-term circulation.<\/p>\n\n\n\n<p><strong>Why it matters:<\/strong><br>DHEA-S gives insight into adrenal function and androgenic tone. Low levels may reflect chronic stress, aging, or poor adrenal output. Elevated levels may indicate PCOS (in women), adrenal overactivity, or overuse of DHEA supplements. It\u2019s also useful for assessing whether your body has the raw materials to support testosterone production.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-cortisol\">Cortisol<\/h3>\n\n\n\n<p>Cortisol is a glucocorticoid hormone made by the adrenal glands in response to stress. It&#8217;s regulated by the HPA axis \u2014 the feedback loop between your hypothalamus (brain), pituitary gland, and adrenal glands. It follows a natural rhythm: high in the morning to wake you up, low in the evening to help you wind down.<\/p>\n\n\n\n<p>Cortisol raises blood sugar, controls inflammation, and helps your body respond to physical or emotional stress.<\/p>\n\n\n\n<p><strong>Why it matters:<\/strong><br>Too much cortisol \u2014 from chronic stress, poor sleep, or overtraining \u2014 can blunt testosterone, disrupt recovery, and increase abdominal fat. Too little cortisol can leave you feeling sluggish, foggy, and fatigued. Flattened daily cortisol patterns can signal <strong>HPA axis dysfunction<\/strong>, sometimes referred to as adrenal fatigue.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-luteinizing-hormone-lh\">Luteinizing hormone (LH)<\/h3>\n\n\n\n<p>LH is made by the pituitary gland, a small organ at the base of your brain. It&#8217;s triggered by GnRH (gonadotropin-releasing hormone) from the hypothalamus. LH controls reproductive hormone production:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In men: LH stimulates <strong>Leydig cells<\/strong> in the testes to make testosterone.<\/li>\n\n\n\n<li>In women: LH spikes mid-cycle to <strong>trigger ovulation<\/strong> \u2014 the release of an egg from the ovary.<\/li>\n<\/ul>\n\n\n\n<p><strong>Why it matters:<\/strong><br>Low LH usually means a brain-level issue \u2014 the pituitary or hypothalamus isn\u2019t sending the right signal. High LH, in contrast, suggests the gonads (testes or ovaries) aren\u2019t responding, so the brain keeps trying to compensate. In women, consistently high LH is often linked to PCOS. In men, it can indicate testicular damage.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-follicle-stimulating-hormone-fsh\">Follicle-stimulating hormone (FSH)<\/h3>\n\n\n\n<p>FSH is another hormone made by the pituitary gland. It works alongside LH to regulate fertility:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In men: FSH acts on <strong>Sertoli cells<\/strong> in the testes to support sperm development.<\/li>\n\n\n\n<li>In women: FSH helps <strong>grow and mature ovarian follicles<\/strong>, which eventually release an egg.<\/li>\n<\/ul>\n\n\n\n<p><strong>Why it matters:<\/strong><br>FSH tells you how well the brain is communicating with the reproductive system. High levels in men may mean the testes aren\u2019t working properly. In women, rising FSH is a classic sign of declining ovarian reserve \u2014 often seen in perimenopause. Low FSH in either sex may point to hypothalamic or pituitary suppression, possibly from stress or undernutrition.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-prolactin\">Prolactin<\/h3>\n\n\n\n<p>Prolactin is mainly known for its role in milk production in women after childbirth. But it\u2019s also present in men and non-pregnant women, where it helps regulate reproductive hormones<\/p>\n\n\n\n<p><strong>Why it matters:<\/strong><br>High prolactin suppresses GnRH, the hormone that triggers both LH and FSH. This can lower testosterone in men and disrupt ovulation in women. Elevated prolactin is often caused by stress, certain medications (like antidepressants or antipsychotics), or a prolactinoma \u2014 a benign tumor in the pituitary gland.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-female-only-hormones\">Female-only hormones<\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/06\/Gender-and-Sleep-1024x576.jpg\" alt=\"Gender and sleep\" class=\"wp-image-49850\" srcset=\"https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/06\/Gender-and-Sleep-1024x576.jpg 1024w, https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/06\/Gender-and-Sleep-300x169.jpg 300w, https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/06\/Gender-and-Sleep-768x432.jpg 768w, https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/06\/Gender-and-Sleep-1536x864.jpg 1536w, https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/06\/Gender-and-Sleep-2048x1152.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-estradiol-e2\">Estradiol (E2)<\/h3>\n\n\n\n<p>Estradiol is the primary form of estrogen in women of reproductive age. It\u2019s made mainly by the ovaries and plays a key role in regulating the menstrual cycle, maintaining bone density, supporting mood, and modulating fat distribution.<\/p>\n\n\n\n<p><strong>Why it matters:<\/strong><br>Low estradiol can cause irregular periods, low libido, hot flashes, and bone loss. High levels might suggest estrogen dominance, which can lead to symptoms like bloating, breast tenderness, or heavy periods. Because estradiol fluctuates across the menstrual cycle, test timing is crucial \u2014 day 3 (early follicular phase) or day 21 (luteal phase) gives the most actionable data.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-anti-mullerian-hormone-amh\">Anti-M\u00fcllerian hormone (AMH)<\/h3>\n\n\n\n<p>AMH is produced by granulosa cells in ovarian follicles. It reflects how many immature eggs (follicles) are still available \u2060\u2013 making it a reliable marker of ovarian reserve.<\/p>\n\n\n\n<p><strong>Why it matters:<\/strong><br>AMH helps assess fertility potential, especially when planning for pregnancy or evaluating egg freezing. Low AMH suggests fewer remaining follicles, while high AMH is common in PCOS, where many follicles start to grow but don\u2019t mature or ovulate. AMH is unique in that it stays stable throughout the cycle \u2060\u2013 so it doesn\u2019t matter when you test it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-why-these-hormones-matter\">Why these hormones matter <\/h2>\n\n\n\n<p>Hormones don\u2019t work in isolation. The levels of one hormone influence others through feedback loops between your brain, adrenal glands, and reproductive organs. For example:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Low testosterone? Check LH and SHBG to understand the cause.<\/li>\n\n\n\n<li>Irregular cycles? Look at FSH, LH, estradiol, and AMH together.<\/li>\n\n\n\n<li>Low energy and poor recovery? DHEA-S and cortisol might hold the answer.<\/li>\n<\/ul>\n\n\n\n<p>By measuring these key hormones together, Blood Vision helps map how your endocrine system is performing \u2060\u2013 and where intervention might help.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A clear explainer of the key hormones tested in Ultrahuman\u2019s Blood Vision panel \u2014 what each one does, why it matters, and how high or low levels can affect energy, mood, fertility, and recovery. Includes a structured summary for quick reference.<\/p>\n","protected":false},"author":9,"featured_media":50044,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[44,20],"tags":[],"class_list":["post-50060","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biomarkers","category-womens-health"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3 (Yoast SEO v25.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hormones explained: what blood testing can reveal about your health - Ultrahuman<\/title>\n<meta name=\"description\" content=\"A clear explainer of the key hormones tested in Ultrahuman\u2019s Blood Vision panel \u2014 and levels can affect energy, mood, fertility, and recovery\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hormones explained: what blood testing can reveal about your health\" \/>\n<meta property=\"og:description\" content=\"A clear explainer of the key hormones tested in Ultrahuman\u2019s Blood Vision panel \u2014 and levels can affect energy, mood, fertility, and recovery\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/\" \/>\n<meta property=\"og:site_name\" content=\"Ultrahuman\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ultrahumanhq\" \/>\n<meta property=\"article:published_time\" content=\"2025-08-04T06:03:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/07\/68219445f9adebb0449a4432_fig-3-p-1080.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"584\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Team Ultrahuman\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@UltrahumanHQ\" \/>\n<meta name=\"twitter:site\" content=\"@UltrahumanHQ\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Team Ultrahuman\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/\"},\"author\":{\"name\":\"Team Ultrahuman\",\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/#\/schema\/person\/47e73966094408ddf4ebb9febb348e27\"},\"headline\":\"Hormones explained: what blood testing can reveal about your health\",\"datePublished\":\"2025-08-04T06:03:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/\"},\"wordCount\":1377,\"publisher\":{\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/#organization\"},\"image\":{\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/blog.ultrahuman.com\/wp-content\/uploads\/2025\/07\/68219445f9adebb0449a4432_fig-3-p-1080.jpg\",\"articleSection\":[\"Biomarkers\",\"Women\u2019s Health\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/\",\"url\":\"https:\/\/blog.ultrahuman.com\/blog\/hormones-explained-what-blood-testing-can-reveal-about-your-health\/\",\"name\":\"Hormones explained: what blood testing can reveal about your health - 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